Education
Education
- 1964-68, University of Oregon, B.S., Biology
- 1969-73, University of Oregon Medical School, M.D., Medicine
Residencies
- 1973-74, Baltimore City Hospital, Intern, Medicine
- 1974-79, Tufts-New England Medical Center, Resident, Surgery
Fellowships
Start Year
1983
End Year
1984
Postdoctoral Training
- 2004, Kaiser Permanente - Endovascular Mini Fellowship, Fellow, Surgery, (Vascular)
Board Certifications
- American Board of Surgery, 1981
- American Board of Surgery, Vascular Surgery, 1990
Clinical Expertise
Abdominal Aortic Aneurysm
Carotid Artery Disease
Chronic Venous Insufficiency
Complex Limb Revascularization
Critical Limb Ischemia
Deep Vein Thrombosis
Diabetic Vascular Disease
Dialysis Access
Endovascular Aneurysm Repair
Mesenteric Artery Disease
Peripheral Artery Disease
Thoracic Aortic Aneurysm
Thoracic Outlet Syndrome
Varicose Veins
Vascular Malformations
Clinical Trials
- Related Conditions: Abdominal Aortic Aneurysm, Aneurysm| Start Date: | End Date:
Program Affiliations
Chief, Vascular Surgery Service - San Francisco VA Medical Center
Grants and Funding
- LIPOPROTEIN ISOLATION FROM SURGICAL SPECIMENS AND PLASMA | NIH | 1988-07-01 - 1993-06-30 | Role: Principal Investigator
- LIPOPROTEIN ISOLATION FROM SURGICAL SPECIMENTS AND PLASM | NIH | 1986-12-01 - 1989-11-30 | Role: Principal Investigator
Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 125
- Vascular Anastomoses and Dissection: A Six-Part Simulation Curriculum for Surgical Residents.| | PubMed
- Assessment of Surgeon Performance of Advanced Open Surgical Skills Using a Microskills-Based Novel Curriculum.| | PubMed
- Eptifibatide bridging therapy for staged carotid artery stenting and cardiac surgery: Safety and feasibility.| | PubMed
- Vascular inflammation in a growing iliac artery aneurysm.| | PubMed
- Ferumoxytol-enhanced magnetic resonance angiography is a feasible method for the clinical evaluation of lower extremity arterial disease.| | PubMed
- Vitamin D deficiency is associated with mortality and adverse vascular access outcomes in patients with end-stage renal disease.| | PubMed
- Invited commentary.| | PubMed
- Inducible ApoE gene repair in hypomorphic ApoE mice deficient in the low-density lipoprotein receptor promotes atheroma stabilization with a human-like lipoprotein profile.| | PubMed
- Assessing the anatomic applicability of the multibranched endovascular repair of thoracoabdominal aortic aneurysm technique.| | PubMed
- Macrophage-specific apoE gene repair reduces diet-induced hyperlipidemia and atherosclerosis in hypomorphic Apoe mice.| | PubMed
- Efficacy and durability of endovascular thoracoabdominal aortic aneurysm repair using the caudally directed cuff technique.| | PubMed
- Apolipoprotein E4 domain interaction accelerates diet-induced atherosclerosis in hypomorphic Arg-61 apoe mice.| | PubMed
- Efficacy of optimal long-term management of multiple cardiovascular risk factors (CVD) on walking and quality of life in patients with peripheral artery disease (PAD): protocol for randomized controlled trial.| | PubMed
- Polyunsaturated fatty acids and peripheral artery disease.| | PubMed
- ApoE suppresses atherosclerosis by reducing lipid accumulation in circulating monocytes and the expression of inflammatory molecules on monocytes and vascular endothelium.| | PubMed
- Do microemboli reach the brain penetrating arteries?| | PubMed
- The distribution and size of ischemic lesions after carotid artery angioplasty and stenting: evidence for microembolization to terminal arteries.| | PubMed
- Preoperative coronary artery revascularization and long-term outcomes following abdominal aortic vascular surgery in patients with abnormal myocardial perfusion scans: a subgroup analysis of the coronary artery revascularization prophylaxis trial.| | PubMed
- Long-term follow-up of neck expansion after endovascular aortic aneurysm repair.| | PubMed
- Atherosclerotic plaque progression in carotid arteries: monitoring with high-spatial-resolution MR imaging--multicenter trial.| | PubMed
- The upside-down zenith stent graft limb.| | PubMed
- Distal filtration versus flow reversal: An ex vivo assessment of the choices for carotid embolic protection.| | PubMed
- Outcome of renal stenting for renal artery coverage during endovascular aortic aneurysm repair.| | PubMed
- Microemboli composed of cholesterol crystals disrupt the blood-brain barrier and reduce cognition.| | PubMed
- Branched stent-grafts: will these become the new standard?| | PubMed
- An experimental model of lacunar infarction: embolization of microthrombi.| | PubMed
- High-resolution CT imaging of carotid artery atherosclerotic plaques.| | PubMed
- Predictors and outcomes of a perioperative myocardial infarction following elective vascular surgery in patients with documented coronary artery disease: results of the CARP trial.| | PubMed
- Endovascular treatment of thoracoabdominal aortic aneurysms.| | PubMed
- Clinical factors associated with long-term mortality following vascular surgery: outcomes from the Coronary Artery Revascularization Prophylaxis (CARP) Trial.| | PubMed
- Atheroembolism during percutaneous renal artery revascularization.| | PubMed
- Postprocedural microembolic events following carotid surgery and carotid angioplasty and stenting.| | PubMed
- Subclinical embolization after carotid artery stenting: new lesions on diffusion-weighted magnetic resonance imaging occur postprocedure.| | PubMed
- MRI of geometric and compositional features of vulnerable carotid plaque.| | PubMed
- Long-term outcome and reintervention after endovascular abdominal aortic aneurysm repair using the Zenith stent graft.| | PubMed
- The effect of magnetic resonance imaging on stainless-steel Z-stent-based abdominal aortic prosthesis.| | PubMed
- Unmasking complicated atherosclerotic plaques on carotid magnetic resonance angiography: a report of three cases.| | PubMed
- Ezetimibe inhibits the incorporation of dietary oxidized cholesterol into lipoproteins.| | PubMed
- Postoperative outcomes for patients undergoing elective revascularization for critical limb ischemia and intermittent claudication: a subanalysis of the Coronary Artery Revascularization Prophylaxis (CARP) trial.| | PubMed
- Adjunctive primary stenting of Zenith endograft limbs during endovascular abdominal aortic aneurysm repair: implications for limb patency.| | PubMed
- The role of dietary oxidized cholesterol and oxidized fatty acids in the development of atherosclerosis.| | PubMed
- Aortoiliac occlusive disease in patients with known or suspected peripheral vascular disease: safety and efficacy of gadofosveset-enhanced MR angiography--multicenter comparative phase III study.| | PubMed
- Atheroemboli during renal artery angioplasty: an ex vivo study.| | PubMed
- Credentialing for carotid artery stenting.| | PubMed
- Coronary-artery revascularization before elective major vascular surgery.| | PubMed
- Transport of contrast agents in contrast-enhanced magnetic resonance angiography.| | PubMed
- Current status of carotid imaging by MRA.| | PubMed
- Impact of surgeon and surgical center characteristics on choice of permanent vascular access.| | PubMed
- Cerebral ischemia and infarction from atheroemboli <100 microm in Size.| | PubMed
- Contrast material-enhanced MRA overestimates severity of carotid stenosis, compared with 3D time-of-flight MRA.| | PubMed
- Double-lumen carotid plaque: a morbid configuration.| | PubMed
- Biochemical characterization of atherosclerotic plaque constituents using FTIR spectroscopy and histology.| | PubMed
- Oxidized cholesterol in the diet is a source of oxidized lipoproteins in human serum.| | PubMed
- Hepatic endosomal trafficking of lipoprotein-bound endotoxin in rats.| | PubMed
- Rupture rate of large abdominal aortic aneurysms in patients refusing or unfit for elective repair.| | PubMed
- Immediate repair compared with surveillance of small abdominal aortic aneurysms.| | PubMed
- Expansion rates and outcomes for the 3.0-cm to the 3.9-cm infrarenal abdominal aortic aneurysm.| | PubMed
- Major carotid plaque surface irregularities correlate with neurologic symptoms.| | PubMed
- Structure of plaque at carotid bifurcation: high-resolution MRI with histological correlation.| | PubMed
- Endoleak after endovascular repair of abdominal aortic aneurysm.| | PubMed
- Detection of clinically silent infarcts after carotid endarterectomy by use of diffusion-weighted imaging.| | PubMed
- Atheroemboli to the brain: size threshold for causing acute neuronal cell death.| | PubMed
- Oxidized cholesterol in the diet accelerates the development of atherosclerosis in LDL receptor- and apolipoprotein E-deficient mice.| | PubMed
- Endovascular aneurysm repair in high-risk patients.| | PubMed
- Oxidized cholesterol in the diet accelerates the development of aortic atherosclerosis in cholesterol-fed rabbits.| | PubMed
- Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for atherosclerotic lesion development.| | PubMed
- Exposure to cigarette smoke delays the plasma clearance of chylomicrons and chylomicron remnants in rats.| | PubMed
- A blinded trial of local recombinant tissue factor pathway inhibitor versus either local or systemic heparin in a vein bypass model.| | PubMed
- Rabbit aorta and human atherosclerotic lesions hydrolyze the sphingomyelin of retained low-density lipoprotein. Proposed role for arterial-wall sphingomyelinase in subendothelial retention and aggregation of atherogenic lipoproteins.| | PubMed
- Sepsis increases endocytosis of endotoxin into hepatocytes.| | PubMed
- Oxidized lipids in the diet accelerate the development of fatty streaks in cholesterol-fed rabbits.| | PubMed
- Oxidized lipids in the diet are incorporated by the liver into very low density lipoprotein in rats.| | PubMed
- Triglyceride-rich lipoproteins prevent septic death in rats.| | PubMed
- Role for circulating lipoproteins in protection from endotoxin toxicity.| | PubMed
- Assessment of carotid artery stenosis by ultrasonography, conventional angiography, and magnetic resonance angiography: correlation with ex vivo measurement of plaque stenosis.| | PubMed
- Triglyceride-rich lipoproteins improve survival when given after endotoxin in rats.| | PubMed
- Oxidized lipids in the diet are a source of oxidized lipid in chylomicrons of human serum.| | PubMed
- Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque.| | PubMed
- Endotoxin and cytokines increase hepatic messenger RNA levels and serum concentrations of apolipoprotein J (clusterin) in Syrian hamsters.| | PubMed
- The protective effect of serum lipoproteins against bacterial lipopolysaccharide.| | PubMed
- Comparison of cardiac morbidity rates between aortic and infrainguinal operations: two-year follow-up. Study of Perioperative Ischemia Research Group.| | PubMed
- Limb salvage and wound coverage in patients with large ischemic ulcers: a multidisciplinary approach with revascularization and free tissue transfer.| | PubMed
- Chylomicrons enhance endotoxin excretion in bile.| | PubMed
- Cigarette smoke alters chylomicron metabolism in rats.| | PubMed
- The effect of oxidized lipids in the diet on serum lipoprotein peroxides in control and diabetic rats.| | PubMed
- Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death.| | PubMed
- Effect of dietary lipid peroxides on metabolism of serum chylomicrons in rats.| | PubMed
- Adverse effects of aspirin in the treatment of asymptomatic carotid artery stenosis. The VA Cooperative Asymptomatic Carotid Artery Stenosis Study Group.| | PubMed
- Magnetic resonance angiography of the carotid artery combining two- and three-dimensional acquisitions.| | PubMed
- Assessment of carotid artery stenosis by MR angiography: comparison with x-ray angiography and color-coded Doppler ultrasound.| | PubMed
- The effect of lipid lowering on the incidence of recurrent carotid stenosis.| | PubMed
- Inhibition of injury induced intimal hyperplasia by saralasin in rats.| | PubMed
- Relation of plasma lipid and apoprotein levels to progressive intimal hyperplasia after arterial endarterectomy.| | PubMed
- Chylomicron and chylomicron remnant metabolism in STZ-induced diabetic rats.| | PubMed
- Comparison of cardiac morbidity between aortic and infrainguinal operations. Study of Perioperative Ischemia (SPI) Research Group.| | PubMed
- Regulation of hepatic lipid metabolism by cytokines that induce the acute phase response.| | PubMed
- Chylomicrons can inhibit endotoxin activity in vitro.| | PubMed
- Connective tissue proteinases and inhibitors in abdominal aortic aneurysms. Involvement of the vasa vasorum in the pathogenesis of aortic aneurysms.| | PubMed
- A prospective randomized trial of autologous platelet-derived wound healing factors for treatment of chronic nonhealing wounds: a preliminary report.| | PubMed
- Chronic visceral ischemia. Three decades of progress.| | PubMed
- Detection of endotoxin in triglyceride-rich lipoproteins in vitro.| | PubMed
- Lower-extremity vascular grafts placed for peripheral vascular disease: prospective evaluation with duplex Doppler sonography.| | PubMed
- Dietary eicosapentaenoic acid and docosahexaenoic acid from fish oil. Their incorporation into advanced human atherosclerotic plaques.| | PubMed
- Simultaneous resection of renal carcinoma and abdominal aortic aneurysm.| | PubMed
- Basic data related to lipid abnormalities in peripheral vascular disease.| | PubMed
- The "natural history" of segmental wall motion abnormalities in patients undergoing noncardiac surgery. S.P.I. Research Group.| | PubMed
- Human very low density lipoproteins and chylomicrons can protect against endotoxin-induced death in mice.| | PubMed
- Testosterone regulates metabolism of plasma chylomicrons in rats.| | PubMed
- Recurrent carotid stenosis: a consequence of local or systemic factors? The influence of unrepaired technical defects.| | PubMed
- Recombinant human tissue-type plasminogen activator is an effective agent for thrombolysis of peripheral arteries and bypass grafts: preliminary report.| | PubMed
- Saphenous vein bypass to pedal arteries. An aggressive strategy for foot salvage.| | PubMed
- Identification of aortic thrombus by magnetic resonance imaging.| | PubMed
- "Angiography" by magnetic resonance imaging: detailed vascular anatomy without ionizing radiation or contrast media.| | PubMed
- Particle size distribution of lipoproteins from human atherosclerotic plaque: a preliminary report.| | PubMed
- Preoperative balloon-tipped catheter placement for proximal control in visceral artery aneurysm surgery.| | PubMed
- Comparative effects of hypertension and nicotine on injury-induced myointimal thickening.| | PubMed
- Hypercholesterolemia and early restenosis after carotid endarterectomy.| | PubMed
- Recurrent carotid stenosis: operative strategy and late results.| | PubMed
- Cholesterol lowering with total parenteral nutrition (TPN)| | PubMed
- Ischemia of the upper extremity: significance of proximal arterial disease.| | PubMed
- Durability of endarterectomy and antegrade grafts in the treatment of chronic visceral ischemia.| | PubMed
- Composition and metabolism of symptomatic distal aortic plaque.| | PubMed
- Direct revascularization for occlusion of the trunks of the aortic arch.| | PubMed
- Lipids of human atherosclerotic plaques and xanthomas: clues to the mechanism of plaque progression.| | PubMed
- Colestipol plus nicotinic acid in treatment of heterozygous familial hypercholesterolaemia.| | PubMed